The PE GenieFluor 594 Anti-Mouse CD11a Antibody (FD441-8) is a cutting-edge tool for researchers studying immune responses in mice. This highly specific antibody, validated for use in flow cytometry and immunofluorescence applications, targets the CD11a protein, a key cell adhesion molecule involved in immune cell interactions.CD11a, also known as integrin alpha L, is a crucial component of the leukocyte function-associated antigen-1 (LFA-1) complex, playing a vital role in cell adhesion, migration, and signaling within the immune system. By using the PE GenieFluor 594 Anti-Mouse CD11a Antibody, researchers can accurately detect and analyze CD11a expression on various immune cell populations, shedding light on their activation and functionality.
This antibody is an essential tool for investigating immune responses, inflammation, and autoimmune disorders in mouse models. Its high specificity and reliability make it a valuable asset for immunologists, cancer researchers, and scientists exploring the intricacies of the immune system. Explore the complex world of immune cell interactions with the PE GenieFluor 594 Anti-Mouse CD11a Antibody (FD441-8).
Integrin alpha-L;Itgal;CD11 antigen-like family member A;LFA-1A;Lymphocyte antigen 15;Ly-15;CD11a;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
PE/Genie Fluor 594 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
PE/Genie Fluor594
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P24063
Gene ID:
16408
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD11a is a 180 kD glycoprotein, also known as αL integrin, LFA-1 α, Ly-15, or Ly-21. It is a member of the integrin family, primarily expressed on lymphocytes, monocytes/macrophages, and granulocytes. In association with CD18, the CD11a/CD18 complex forms LFA-1. CD11a plays an important role in intercellular adhesion and costimulation by binding its ligands, ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).