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PE/GenieFluor 594 Anti-Human CD86 Antibody [BU63] (AGEL3182)

SKU:
AGEL3182
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, k
Clone:
BU63
Conjugation:
PE/AF594
€209 - €669

Description

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PE/GenieFluor 594 Anti-Human CD86 Antibody [BU63]

The PE-GenieFluor 594 Anti-Human CD86 Antibody (BU63) offered by AssayGenie is a cutting-edge tool for researchers studying the CD86 cell surface molecule. This antibody, optimized for use in flow cytometry applications, is specifically designed to target human CD86, a critical co-stimulatory molecule involved in immune responses.The BU63 antibody, meticulously developed and validated by AssayGenie, is highly specific and sensitive, ensuring reliable and accurate results in experimental settings. By binding to CD86, this antibody enables precise detection and analysis of CD86 expression in various cell types, making it an invaluable asset for investigations in immunology, vaccine development, and autoimmune disease research.

CD86, also known as B7-2, plays a pivotal role in T cell activation and immune regulation by providing co-stimulatory signals necessary for effective immune responses. Understanding the expression and function of CD86 is essential for unraveling the complexities of immune activation and identifying potential therapeutic targets for immune-related disorders.With its exceptional quality and performance, the PE-GenieFluor 594 Anti-Human CD86 Antibody (BU63) from AssayGenie is a versatile tool that empowers researchers to explore the intricate mechanisms of immune regulation and develop innovative strategies for manipulating immune responses.

Product Title:PE/GenieFluor 594 Anti-Human CD86 Antibody [BU63]
SKU:AGEL3182
Size:20 Tests, 100 Tests, 200 Tests
Clone No:BU63
Synonyms:T-lymphocyte activation antigen CD86;Cd86;Activation B7-2 antigen;Early T-cell costimulatory molecule 1;ETC-1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE/Genie Fluor 594 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE/Genie Fluor594
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P42081
Gene ID:942
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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