The PE GenieFluor 594 Anti-Human CD81 Antibody (1.3.3.22) offered by Assay Genie is a valuable tool for researchers studying CD81, a cell surface protein known to be involved in various cellular processes. This antibody, specifically designed for binding to the CD81 protein in human samples, is ideal for use in flow cytometry and other immunofluorescence-based applications.CD81, also known as the target of the anti-CD81 antibody, is a member of the tetraspanin superfamily and is involved in cell adhesion, migration, and signal transduction. Its presence in various cell types makes it a versatile marker for studying cell biology, immunology, and infectious diseases.
The use of the PE GenieFluor 594 Anti-Human CD81 Antibody (1.3.3.22) allows for the precise detection and analysis of CD81 expression, enabling researchers to delve deeper into its functions and significance in cellular processes.With its high specificity and reliability, this antibody is a valuable resource for research projects focused on understanding the role of CD81 in health and disease. Whether investigating viral entry mechanisms, exploring cellular interactions, or studying membrane dynamics, the PE GenieFluor 594 Anti-Human CD81 Antibody (1.3.3.22) provides researchers with a powerful tool to advance their scientific inquiries.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P60033
Gene ID:
975
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD81 is a 26 kD non-glycosylated member of the tetraspanin superfamily (TM4SF), also known as TAPA-1 (target of an antiproliferative antibody). CD81 is expressed on T and B cells, NK cells, monocytes, dendritic cells, thymocytes, endothelial cells, and fibroblasts. It also has low levels of expression on granulocytes. CD81 induces B cell adhesion via VLA-4 integrin and has been shown to play a role in early T cell development. CD81 associates with several other cell-surface proteins in a multimolecular complex, including CD19, CD21, CD20, CD37, CD53, and CD82 in B cells, and CD4, CD8 and CD82 in T cells.