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PE/GenieFluor 594 Anti-Human CD7 Antibody [124-1D1] (AGEL3224)

SKU:
AGEL3224
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, k
Clone:
124-1D1
Conjugation:
PE/AF594
$263 - $923
Frequently bought together:

Description

PE/GenieFluor 594 Anti-Human CD7 Antibody [124-1D1]

The PE-GenieFluor 594 Anti-Human CD7 Antibody (124-1D1) offered by AssayGenie is a crucial tool for researchers studying CD7, a cell surface antigen that plays a pivotal role in immune cell development and function. This antibody, specifically designed for use in flow cytometry applications, is optimized for detecting human CD7 protein with high sensitivity and specificity.CD7 is a marker found on T cells, natural killer cells, and hematopoietic stem cells, making it a valuable target for investigating immune system function and cell differentiation processes. The PE-GenieFluor 594 Anti-Human CD7 Antibody (124-1D1) enables precise identification and analysis of CD7-expressing cells in various biological samples, facilitating research in immunology, hematology, and cancer biology.

By utilizing this antibody, researchers can explore the role of CD7 in immune cell signaling, activation, and maturation, providing insights into diseases such as leukemia, lymphoma, and autoimmune disorders. The accurate detection and quantification of CD7 expression facilitated by this antibody contribute to advancing our understanding of immune system dynamics and developing targeted therapies for CD7-associated conditions.

Product Name:PE/AF594 Anti-Human CD7 Antibody [124-1D1]
Product Code:AGEL3224
Size:20 Tests, 100 Tests, 200 Tests
Clone No:124-1D1
Synonyms:T-cell antigen CD7, CD7, GP40, T-cell leukemia antigen, T-cell surface antigen Leu-9, TP41, TP41
Reactivity:Human
Host Species:Mouse
Applications:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE/GenieFluor 594 Mouse IgG1, κ Isotype Control [MOPC-21] (AGEL3461)
Conjugation:PE/AF594
Applications:FCM
Recommended Dilution:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage:Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Fluorescent Label:PE/GenieFluor 594 is designed to be excited by the blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 620 nm (e.g., a 610/20 nm bandpass filter).
Shipping:Biological ice pack at 4°C
Form:Liquid
Gene ID:924
Swissprot:P09564
Background Information:CD7 is a 40 kD type I transmembrane glycoprotein also known as gp40. It is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL) and some acute myeloid leukemia (AML) cells. CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 costimulation can induce cytokine secretion and modulate cellular adhesion.

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