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PE/GenieFluor 594 Anti-Human CD62L Antibody [DREG56] (AGEL3145)

SKU:
AGEL3145
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, κ
Clone:
DREG56
Conjugation:
PE/AF594
€139 - €469
Frequently bought together:

Description

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PE/GenieFluor 594 Anti-Human CD62L Antibody [DREG56]

The PE Fluor 594 Anti-Human CD62L Antibody (DREG56) offered by Assay Genie is a crucial tool for research in immunology and related fields. This antibody is specifically designed for the detection and analysis of CD62L, a cell adhesion molecule known for its involvement in immune cell trafficking and activation.The DREG56 antibody, optimized for use in flow cytometry and immunofluorescence applications, is highly reactive with human CD62L samples. It binds specifically to the CD62L protein, allowing for precise identification and examination of this important cell surface marker in a variety of cell types.CD62L, also referred to as L-selectin, plays a pivotal role in lymphocyte recirculation and homing to secondary lymphoid organs.

Its expression pattern and function make it a key player in immune responses, inflammation, and immune cell migration. Therefore, research involving CD62L is crucial for understanding immune system dynamics, inflammatory processes, and immune-related diseases.By utilizing the PE Fluor 594 Anti-Human CD62L Antibody (DREG56), researchers can delve deeper into the mechanisms underlying immune cell trafficking and function, paving the way for advancements in immunology, vaccine development, and therapeutic interventions targeting immune-mediated disorders.

Product Title:PE/GenieFluor 594 Anti-Human CD62L Antibody [DREG56]
SKU:AGEL3145
Size:20 Tests, 100 Tests, 200 Tests
Clone No:DREG56
Synonyms:L-selectin;Sell;CD62 antigen-like family member L;LAM-1;LECAM1;Lymph node homing receptor;Ly-22; CD62L;Lnhr;Ly22;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE/Genie Fluor 594 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE/Genie Fluor594
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P14151
Gene ID:6402
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.

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