The PE GenieFluor® 594 Anti-Human CD57 Antibody (HNK-1) offered by AssayGenie is a cutting-edge tool for researchers investigating CD57, a cell surface marker associated with natural killer cells, and various immune responses. This high-quality antibody is tailored for use in flow cytometry applications, allowing for precise and reliable detection of CD57 in human samples.CD57, also known as HNK-1 antigen, serves as a marker for mature NK cells and memory T cells, playing a pivotal role in immune surveillance and response. Understanding the expression and function of CD57 is essential in unraveling intricate immune processes, making this antibody a valuable asset in immunology, virology, and cancer research.
By specifically targeting CD57, researchers can delve deeper into the mechanisms underlying immune cell interactions and responses in health and disease.The PE GenieFluor® 594 Anti-Human CD57 Antibody (HNK-1) provides researchers with a reliable tool to unlock the mysteries of immune cell populations and their functions. With its exceptional specificity and sensitivity, this antibody is a standout choice for studies aiming to elucidate the role of CD57 in various physiological and pathological conditions. Trust AssayGenie for high-quality antibodies that drive breakthrough discoveries in immunology.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Gene ID:
27087
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD57, also known as HNK-1, NK-1, and Leu-7 is a 100-115 kD oligosaccharide antigenic determinant expressed on a variety of proteins, lipids, and chondroitin sulfate proteoglycans. CD57 is expressed on a subset of peripheral blood lymphocytes, including NK cells and CD8+ T cells, and is also expressed on neural cells and striated muscle. CD57 is not expressed on red blood cells, granulocytes, monocytes, or platelets. While the function of CD57 is unknown, binding to L-selectin, P-selectin, and a fragment of laminin suggests that CD57 may be involved in cell-matrix interactions. CD57 is increased in some disease states associated with CD4/CD8 imbalances (AIDS, autoimmune disease, viral infections, and allograft transplants).