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PE/GenieFluor 594 Anti-Human CD54 Antibody [15.2] (AGEL3201)

SKU:
AGEL3201
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, k
Clone:
15.2
Conjugation:
PE/AF594
€209 - €709
Frequently bought together:

Description

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PE/GenieFluor 594 Anti-Human CD54 Antibody [15.2]

The PE GenieFluorâ„¢ 594 Anti-Human CD54 Antibody (15-2) offered by Assay Genie is a powerful tool for researchers studying CD54, also known as intercellular adhesion molecule-1 (ICAM-1). This antibody is specifically designed for use in flow cytometry, immunofluorescence, and other cell-based assays to detect and analyze CD54 expression in human samples.CD54 is a cell surface glycoprotein that plays a key role in immune responses, particularly in cell adhesion and migration processes during inflammation and immune activation. The PE-conjugated Anti-Human CD54 Antibody (15-2) enables precise and reliable detection of CD54 expression levels, allowing researchers to investigate its functions in various cell types and physiological conditions.

By targeting CD54, researchers can explore its involvement in important biological processes such as leukocyte recruitment, antigen presentation, and immune cell signaling. Understanding the regulation and signaling pathways associated with CD54 is essential for unraveling its implications in inflammatory diseases, immune disorders, and autoimmune conditions.With its high specificity, sensitivity, and validated performance in various experimental techniques, the PE GenieFluorâ„¢ 594 Anti-Human CD54 Antibody (15-2) from Assay Genie is a valuable tool for advancing research in immunology, inflammation, and related fields. Unlock the mysteries of CD54 function and explore its potential as a therapeutic target with this reliable antibody.

Product Title:PE/GenieFluor 594 Anti-Human CD54 Antibody [15.2]
SKU:AGEL3201
Size:20 Tests, 100 Tests, 200 Tests
Clone No:15.2
Synonyms:Intercellular adhesion molecule 1;Icam1;MALA-2;MyD10;CD54;Icam-1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE/Genie Fluor 594 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE/Genie Fluor594
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P05362
Gene ID:3383
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD54 is a 85-110 kD type I transmembrane protein also known as ICAM-1. It is expressed on activated endothelial cells, high endothelial venules, T and B cells, monocytes/macrophages, granulocytes, and dendritic cells. The expression of ICAM-1 can be released from the cell surface. CD54 plays a role in cellular adhesion and is involved in inflammation and leukocyte extravasation. CD54 has also been shown to be the major cellular receptor for rhinovirus. ICAM-1 binds to CD11a/CD18 (LFA-1), CD11b/CD18 (Mac-1), CD11c/CD18 (p150, 95) as well as hyaluronan and fibrinogen.

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