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PE/GenieFluor 594 Anti-Human CD49d Antibody [9F10] (AGEL3267)

SKU:
AGEL3267
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, k
Clone:
9F10
Conjugation:
PE/AF594
€269 - €889
Frequently bought together:

Description

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PE/GenieFluor 594 Anti-Human CD49d Antibody [9F10]

The PE GenieFluor 594 Anti-Human CD49d Antibody (9F10) offered by AssayGenie is a cutting-edge tool for researchers exploring the role of CD49d in cell adhesion and migration processes. This antibody is specifically designed for use in flow cytometry applications, allowing for precise detection and analysis of CD49d expression on human cells. CD49d, also known as integrin alpha-4, is a crucial cell surface receptor involved in mediating cell-cell and cell-matrix interactions, making it a key player in immune responses, inflammation, and tissue repair.

By targeting CD49d with this highly sensitive antibody, researchers can gain insights into the mechanisms underlying various physiological and pathological processes.Whether investigating the role of CD49d in immune cell trafficking, cancer metastasis, or inflammatory diseases, the PE GenieFluor 594 Anti-Human CD49d Antibody (9F10) provides researchers with a powerful tool to advance their understanding of cell adhesion dynamics. Trust AssayGenie for reliable reagents that enable groundbreaking research in immunology, oncology, and beyond.

Product Title:PE/GenieFluor 594 Anti-Human CD49d Antibody [9F10]
SKU:AGEL3267
Size:20 Tests, 100 Tests, 200 Tests
Clone No:9F10
Synonyms:Integrin alpha-4;CD49 antigen-like family member D;Integrin alpha-IV;VLA-4 subunit alpha;CD49d;ITGA4;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE/Genie Fluor 594 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE/Genie Fluor594
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P13612
Gene ID:3676
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD49d is a 150 kD α integrin chain known as α4 integrin or VLA-4 α chain. It forms a heterodimer with either integrin β1 (α4β1, VLA-4) or β7 (α4β7). CD49d is expressed broadly on T lymphocytes, B lymphocytes, monocytes, thymocytes, eosinophils, basophils, mast cells, NK cells, dendritic cells, and some non-hematopoietic cells, but not on normal red blood cells, platelets or neutrophils. VLA-4 binds to VCAM-1 (CD106) and fibronectin. α4β7 is the receptor for VCAM-1 and MAdCAM-1. CD49d participates in mononuclear cell trafficking to endothelial sites of inflammation and has roles in cell-cell interactions and cell adhesion to extracellular matrices. CD49d is involved in lymphocyte migration, T cell activation, and hematopoietic stem cell differentiation. CD49d is a marker to isolate pure populations of Treg cells due to its absence on Foxp3+ cells.

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