The PE-GenieFluor 594 Anti-Human CD48 Antibody (156-4H9) offered by Assay Genie is a cutting-edge tool for research involving the CD48 cell surface molecule. This antibody, designed for use with human samples, is ideal for studies in immunology and related fields. Its specificity and high reactivity make it well-suited for various applications, including flow cytometry and immunofluorescence. The CD48 molecule, known for its role in immune regulation and cell communication, is a key player in immune responses and its study is crucial for understanding diseases such as autoimmune disorders and cancer.
Researchers can rely on this antibody to enable precise detection and analysis of CD48 protein in diverse cell types, advancing knowledge and potential therapeutic strategies in immunology research.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P09326
Gene ID:
962
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD48 is a 40-47 kD GPI-anchored membrane protein, also known as Blast-1 and HuLy-m3. It is a member of the CD2 family that contains 2 IgSF domains and is widely expressed on both resting and activated hematopoietic cells with the exception of granulocytes, platelets, and erythrocytes. CD48 binds to CD2 at a considerably (>100-fold) lower affinity than CD58. It is thought to contribute to T cell activation. The cytoplasmic tail of CD48 has been shown to bind to the kinases Lck and Fyn.