The PE-GenieFluor 594 Anti-Human CD44 Antibody (P2A1) is a cutting-edge tool for researchers studying CD44, a cell surface glycoprotein involved in cell adhesion and migration processes. This antibody, specifically designed for use in human samples, offers high reactivity and specificity, making it a reliable choice for various immunofluorescence and flow cytometry applications.CD44 is a multifunctional molecule known for its role in cell-cell interactions, lymphocyte homing, and tumor metastasis. By targeting CD44 with the PE-GenieFluor 594 Anti-Human CD44 Antibody (P2A1), researchers can effectively visualize and analyze the expression of this protein in different cell populations.
This antibody's compatibility with fluorescence microscopy and flow cytometry techniques enables detailed investigations into CD44's involvement in processes like inflammation, metastasis, and stem cell migration.With its superior performance and validated specificity, the PE-GenieFluor 594 Anti-Human CD44 Antibody (P2A1) is an essential tool for advancing research in immunology, oncology, and regenerative medicine. By unlocking the secrets of CD44 dynamics and function, researchers can gain valuable insights into disease mechanisms and potential therapeutic targets for conditions such as cancer, autoimmune disorders, and tissue regeneration.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P16070
Gene ID:
960
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from a low or mid level of intensity to high expression levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.