The PE-GenieFluor 594 Anti-Human CD37 Antibody (IPO-24) from Assay Genie is a cutting-edge tool for researchers studying the CD37 protein, a cell surface antigen associated with various immune functions. This highly specific antibody is meticulously designed to target human CD37, facilitating precise detection and analysis in a range of cell types. With its optimized formulation, researchers can confidently explore the role of CD37 in immunology and cancer research applications.CD37, a transmembrane glycoprotein, is known for its involvement in B cell signaling and development, making it a key player in immune response modulation.
By utilizing the PE-GenieFluor 594 Anti-Human CD37 Antibody (IPO-24), researchers can delve into the mechanisms underlying B cell function, immune regulation, and potential implications in disease states such as leukemia and lymphoma. This antibody opens up new avenues for investigating CD37-related pathways and developing targeted therapies in the realm of immunotherapy.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P11049
Gene ID:
951
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD37 is a 40-52 kD type II transmembrane protein, also known as tetraspanin-26. It is a member of the transmembrane tetraspanin family. It can interact with integrins and other transmembrane 4 superfamily members (CD53, CD81, CD82). CD37 is expressed predominantly on B cells; low expression is detected on T cells and myeloid cells. No expression is reported on NK cells and plasma cells. It is involved in regulation of T cell proliferation.