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PE/GenieFluor 594 Anti-Human CD35 Antibody [E11] (AGEL3221)

SKU:
AGEL3221
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, k
Clone:
E11
Conjugation:
PE/AF594
$251 - $851
Frequently bought together:

Description

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PE/GenieFluor 594 Anti-Human CD35 Antibody [E11]

The PE-GenieFluor 594 Anti-Human CD35 Antibody (E11) available at AssayGenie is a potent tool for immunofluorescence and flow cytometry studies focusing on CD35, a key protein involved in immune response regulation. This antibody, specifically developed for use with human samples, exhibits high reactivity and specificity, ensuring accurate and reliable results in research applications.CD35, also known as complement receptor 1 (CR1), plays a pivotal role in the recognition and clearance of immune complexes and apoptotic cells, contributing to maintaining immune homeostasis. By binding to CD35, the PE-GenieFluor 594 Anti-Human CD35 Antibody (E11) enables precise identification and analysis of CD35 expression in various cell types, facilitating investigations in immunology, autoimmune diseases, and inflammatory disorders.

Understanding the functions and expression patterns of CD35 is crucial in unraveling its implications in immune regulation and its potential as a therapeutic target in conditions such as autoimmune disorders, infectious diseases, and inflammatory responses. The use of the PE-GenieFluor 594 Anti-Human CD35 Antibody (E11) empowers researchers to delve deeper into the intricate mechanisms of immune modulation and opens avenues for innovative approaches in disease management and treatment strategies.

Product Title:PE/GenieFluor 594 Anti-Human CD35 Antibody [E11]
SKU:AGEL3221
Size:20 Tests, 100 Tests, 200 Tests
Clone No:E11
Synonyms:Complement receptor type 1;CR1;C3b/C4b receptor;CD35;CR1;C3BR;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE/Genie Fluor 594 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE/Genie Fluor594
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P17927
Gene ID:1378
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD35 is a type I single chain of glycoprotein, also known as C3b/C4b receptor, Complement Receptor type 1 or CR1. Four molecular weight allotypes (160kD, 190kD, 220kD, and 250kD) have been described. CD35 is expressed on granulocytes, monocytes, B cells, erythrocytes, and follicular dendritic cells, as well as subsets of NK and T cells. CD35 binds complement C3b, C4b, or iC3, and iC4, and plays important roles in both innate and adoptive immune response via mediating phagocytosis by granulocytes and monocytes. CD35 has also been reported to inhibit T-cell proliferation.

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