The PE-GenieFluor 594 Anti-Human CD34 Antibody is a powerful tool designed for the detection and analysis of CD34, a cell surface marker widely used in identifying hematopoietic stem cells and endothelial progenitor cells. This antibody, optimized for use in flow cytometry applications, is raised in rabbits and exhibits high specificity and sensitivity towards human CD34 antigen.CD34 is a key marker in stem cell research, enabling the identification and purification of stem and progenitor cells for various applications, including cell therapy and regenerative medicine.
This antibody binds specifically to CD34-expressing cells, allowing for precise identification and characterization in complex cell populations.The PE-GenieFluor 594 Anti-Human CD34 Antibody is an essential tool for researchers studying hematopoiesis, vascular biology, and stem cell differentiation. Its reliable performance and versatility make it an invaluable asset in advancing our understanding of stem cell biology and developing novel therapeutic strategies for a range of diseases.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P28906
Gene ID:
947
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD34, also known as gp105-120, is a type I monomeric sialomucin-like glycophosphoprotein with an approximate molecular weight of 105-120 kD. Selectively expressed on the majority of hematopoietic stem/progenitor cells, bone marrow stromal cells, capillary endothelial cells, embryonic fibroblasts, and some nervous tissue, CD34 is a commonly used marker to identify human hematopoietic stem/progenitor cells. According to the differential sensitivity to enzymatic cleavage, four groups of epitopes of CD34 have been described. CD34 mediates cell adhesion and lymphocytes homing through binding to L-selectin and E-selectin ligands.