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PE/GenieFluor 594 Anti-Human CD32 Antibody [IV-3] (AGEL3230)

SKU:
AGEL3230
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG2b, k
Clone:
IV-3
Conjugation:
PE/AF594
€259 - €769
Frequently bought together:

Description

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PE/GenieFluor 594 Anti-Human CD32 Antibody [IV-3]

The PE GenieFluor 594 Anti-Human CD32 Antibody (IV.3) is a cutting-edge tool for researchers studying CD32, a key cell surface receptor involved in immune response modulation. This antibody, optimized for use in flow cytometry, is derived from mouse monoclonal origin and exhibits high specificity and sensitivity towards human samples.CD32, also known as FcγRII, plays a crucial role in regulating immune responses by modulating the activity of immune cells. By targeting CD32, researchers can delve into the intricate mechanisms of immune regulation, particularly in the contexts of infectious diseases, autoimmune disorders, and inflammatory conditions.

The precise binding of the PE GenieFluor 594 Anti-Human CD32 Antibody allows for accurate detection and characterization of CD32-expressing cells, offering insights into immune cell function and potential therapeutic targets.Whether investigating immune-mediated pathologies or exploring novel treatment strategies, this antibody provides a valuable resource for elucidating the role of CD32 in immune system dynamics. Its application extends to a range of research fields, including immunology, oncology, and infectious diseases, where a deeper understanding of CD32 function can pave the way for innovative therapeutic interventions.

Product Title:PE/GenieFluor 594 Anti-Human CD32 Antibody [IV-3]
SKU:AGEL3230
Size:20 Tests, 100 Tests, 200 Tests
Clone No:IV-3
Synonyms:Low affinity immunoglobulin gamma Fc region receptor II-b;FCGR2B;IgG Fc receptor II-b;CDw32;Fc-gamma RII-b;Fc-gamma-RIIb;FcRII-b;CD32;FCG2; IGFR2;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2b, κ
Isotype Control:PE/Genie Fluor 594 Mouse IgG2b, κ Isotype Control[MPC-11]
Form:Liquid
Conjugation:PE/Genie Fluor594
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P31994
Gene ID:2212
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).

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