The PE GenieFluor 594 Anti-Human CD29 Antibody (TS2/16) is a valuable tool for research in the field of immunology and cell biology. This antibody is specifically designed to target the CD29 protein, also known as integrin beta-1, which plays a crucial role in cell adhesion and migration processes.The antibody is highly specific to human CD29 and has been validated for use in various applications such as flow cytometry and immunofluorescence. It enables the detection and analysis of CD29 expression in different cell types, providing researchers with valuable insights into cell interactions and signaling pathways.CD29 is involved in diverse biological processes, including cell proliferation, differentiation, and immune response modulation.
Aberrant CD29 expression has been implicated in various diseases, making it an important target for investigation in cancer research, autoimmune disorders, and inflammation-related conditions.By utilizing the PE GenieFluor 594 Anti-Human CD29 Antibody (TS2/16), researchers can gain a better understanding of the functional role of CD29 in health and disease. This antibody promises reliable results and valuable data that can contribute to advancements in biomedical research and potential therapeutic development.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P05556
Gene ID:
3688
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD29 is a 130 kD single chain type I glycoprotein also known as integrin β1, VLA-β chain, or gpIIa. It is broadly expressed on a majority of hematopoietic and non-hematopoietic cells, including leukocytes (although at low level on granulocytes), platelets, fibroblasts, endothelial cells, epithelial cells, and mast cells. CD29 is a member of the integrin family. It is non-covalently associated with integrin α1-α6 chains to form VLA-1 to VLA-6 molecules, respectively. Integrins, which include CD29, bind to several cell surface (e.g. VCAM-1, MadCAM-1) and extracellular matrix molecules. CD29 acts as a fibronectin receptor and is involved in a variety of cell-cell and cell-matrix interactions.