The PE GenieFluor 594 Anti-Human CD1a Antibody (OKT-6) available on www.assaygenie.com is a valuable tool for researchers studying CD1a, a cell surface antigen involved in immune responses and antigen presentation. This antibody, conjugated with PE GenieFluor 594, provides high sensitivity and specificity for human samples, making it ideal for flow cytometry and immunofluorescence applications.CD1a is a marker expressed on dendritic cells and thymocytes, playing a crucial role in presenting lipid antigens to T cells. The OKT-6 antibody specifically targets CD1a, allowing for precise detection and analysis of this protein in diverse cell types and tissues.
By understanding the expression and function of CD1a, researchers can gain insights into immune responses, antigen presentation, and potential therapeutic targets for immune-related disorders.With its high reactivity and specificity, the PE GenieFluor 594 Anti-Human CD1a Antibody (OKT-6) offers a reliable tool for immunology research, vaccine development, and studies related to autoimmune diseases and infectious agents. Explore the versatile applications of this antibody to advance your understanding of immune system mechanisms and cellular interactions.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P06126
Gene ID:
909
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD1a is a 49 kD member of the immunoglobulin superfamily also known as T6 and R4. It is a type I membrane glycoprotein with structural similarities to MHC class I and is non-covalently associated with β2-microglobulin. CD1a plays a role in non-peptide glycolipid antigen presentation to CD1-restricted T cells. It is expressed on cortical double positive and single positive thymocytes, Langerhans cells, and dendritic cells. In addition to antigen presentation, CD1a has been implicated in thymic T cell development.