The PE GenieFluor 594 Anti-Human CD18 Antibody (TS1/18) is a powerful tool for research involving the CD18 protein, an essential component of integrin receptors that play a critical role in cell adhesion and migration. This antibody, specifically designed for human samples, is highly reactive and provides reliable results in flow cytometry and immunofluorescence applications.CD18, also known as integrin beta-2, is a key player in regulating immune cell interactions and responses. By targeting CD18, researchers can investigate processes such as leukocyte adhesion and migration, essential for understanding immune system function in health and disease.
The PE GenieFluor 594 Anti-Human CD18 Antibody enables precise detection and visualization of CD18 expression in various cell types, facilitating in-depth studies in immunology, inflammation, and infectious diseases.With its validated performance and specificity, this antibody is an important tool for exploring the role of CD18 in immune responses and inflammatory conditions. By elucidating the functions of CD18, researchers can gain insights that may drive the development of novel therapeutic strategies for diseases involving dysregulated immune cell behavior.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P05107
Gene ID:
3689
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD18 is a 90-95 kD type I transmembrane protein also known as integrin β2 subunit, LFA-1 β subunit, and β2 integrin. CD18 non-covalently associates with CD11a, CD11b or CD11c. CD18 is expressed on all leukocytes. CD18 and associated α chains function in adhesion and signaling in hematopoietic cells.