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PE/GenieFluor 594 Anti-Human CD16 Antibody [3G8] (AGEL2773)

SKU:
AGEL2773
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, κ
Clone:
3G8
Conjugation:
PE/AF594
€259 - €889
Frequently bought together:

Description

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PE/GenieFluor 594 Anti-Human CD16 Antibody [3G8]

The PE-GenieFluor 594 Anti-Human CD16 Antibody (3G8) from AssayGenie is a powerful tool for researchers studying CD16, a key cell surface marker involved in immune responses and cell-mediated cytotoxicity. This antibody, specifically designed for use in flow cytometry applications, is highly specific to human CD16 and allows for precise detection and analysis of CD16-expressing cells in various biological samples.CD16, also known as FcγRIII receptor, plays a crucial role in mediating antibody-dependent cellular cytotoxicity (ADCC) and is a vital component of the immune system's response to infections, cancer, and autoimmune disorders.

The ability to accurately measure and characterize CD16 expression is essential for understanding the immune response and developing targeted therapies for diseases where CD16 is implicated.With its superior reactivity and specificity, the PE-GenieFluor 594 Anti-Human CD16 Antibody (3G8) offers researchers a reliable tool for investigating the role of CD16 in immune function, disease pathogenesis, and therapeutic development. Trust AssayGenie for high-quality antibodies that enable groundbreaking research in immunology and beyond.

Product Title:PE/GenieFluor 594 Anti-Human CD16 Antibody [3G8]
SKU:AGEL2773
Size:20 Tests, 100 Tests, 200 Tests
Clone No:3G8
Synonyms:FcγRIII;Fc gamma receptor;Fc gamma receptor 3;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE/Genie Fluor 594 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE/Genie Fluor594
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P08637 O75015
Gene ID:941
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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