The HIM6 Polyclonal Antibody (PE-GenieFluor 594 Anti-Human CD147 Antibody) from Assay Genie is a cutting-edge tool for researchers studying CD147, a key cell surface protein associated with various physiological and pathological processes. This antibody, optimized for use in flow cytometry and immunofluorescence applications, is highly specific to human CD147, ensuring accurate and reliable results in experimental settings.CD147, also known as EMMPRIN or Basigin, is a multifunctional molecule involved in diverse cellular functions, including cell adhesion, migration, and signaling. Its overexpression has been linked to various diseases, such as cancer, inflammation, and neurological disorders.
The HIM6 Polyclonal Antibody allows for the precise detection and visualization of CD147 in different cell types, providing insights into its role in disease progression and therapeutic targeting.By targeting CD147 with the HIM6 Polyclonal Antibody, researchers can delve into the mechanisms underlying its involvement in disease pathogenesis and potentially uncover novel therapeutic strategies. This antibody is a valuable asset for investigations in oncology, immunology, and other fields where CD147 serves as a promising biomarker or therapeutic target. Trust Assay Genie's expertise and high-quality reagents to advance your research and uncover the intricacies of CD147 biology.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P35613
Gene ID:
682
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD147, also known as neurothelin or basigin, is a member of the Ig superfamily. It is a 55-65 kD type I transmembrane glycoprotein which is primarily expressed on leukocytes, erythrocytes, platelets, and endothelial cells. CD147 is reported to have a function during embryonal brain development and/or play a role in integrin-mediated adhesion in brain endothelia.