The PE GenieFluor 594 Anti-Human CD11c Antibody (BU15) offered by Assay Genie is a cutting-edge tool for researchers studying the CD11c protein, a marker associated with dendritic cells and certain subsets of lymphocytes. This antibody, meticulously developed for human samples, enables precise and sensitive detection of CD11c in flow cytometry and immunofluorescence applications.CD11c, a transmembrane glycoprotein crucial for antigen presentation and immune response regulation, serves as a key identifier for dendritic cells and other immune cell populations. By utilizing the PE GenieFluor 594 Anti-Human CD11c Antibody (BU15), researchers can uniquely visualize and analyze CD11c-expressing cells, assisting in the investigation of immune cell function, differentiation, and trafficking.
With its high specificity and reliability in detecting CD11c, this antibody is instrumental for research in immunology, infectious diseases, and autoimmune conditions. Unlock the potential of your research with the PE GenieFluor 594 Anti-Human CD11c Antibody (BU15) from Assay Genie, facilitating in-depth exploration of immune cell dynamics and function.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P20702
Gene ID:
3687
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD11c is a 145-150 kD type I transmembrane glycoprotein also known as integrin αX and CR4. CD11c non-covalently associates with integrin β2 (CD18) and is expressed on monocytes/macrophages, dendritic cells, granulocytes, NK cells, and subsets of T and B cells. CD11c has been reported to play a role in adhesion and CTL killing through its interactions with fibrinogen, CD54, and iC3b.