The PE-Cyanine7 Anti-Rat CD45 Antibody (OX-1) from Assay Genie (AGEL3031) is a highly specific and reliable tool for immunological research involving rat CD45, an essential cell surface marker for identifying leukocytes. This antibody is conjugated with PE-Cyanine7, a bright and stable fluorescent dye that allows for multicolor flow cytometry applications.Rat CD45, also known as the leukocyte common antigen, is a crucial marker for characterizing immune cell populations in rat models. The PE-Cyanine7 Anti-Rat CD45 Antibody (OX-1) exhibits strong reactivity and specificity towards rat CD45, enabling precise identification and analysis of leukocyte subsets in various tissues and experimental conditions.
This antibody is validated for use in flow cytometry and immunofluorescence applications, providing researchers with a powerful tool for studying immune cell dynamics, immune response modulation, and disease pathogenesis in rat models. Whether investigating immune cell phenotypes in infectious disease, autoimmune disorders, or inflammatory conditions, the PE-Cyanine7 Anti-Rat CD45 Antibody (OX-1) offers high sensitivity and reproducibility for insightful experimental results.
Product Title:
PE/Cyanine7 Anti-Rat CD45 Antibody [OX-1]
SKU:
AGEL3031
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
OX-1
Synonyms:
Receptor-type tyrosine-protein phosphatase C;Leukocyte common antigen; LCA; T200; Ly-5;Ptprc;
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P04157
Gene ID:
19265
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro.