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PE/Cyanine7 Anti-Rat CD44H Antibody [OX-49] (AGEL3026)

SKU:
AGEL3026
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Rat
Host Species:
Mouse
Isotype:
Mouse IgG2a, κ
Clone:
OX-49
Conjugation:
PE/Cyanine7
€229 - €549
Frequently bought together:

Description

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PE/Cyanine7 Anti-Rat CD44H Antibody [OX-49]

The PE-Cyanine7 Anti-Rat CD44H Antibody (OX-49) from Assay Genie (AGEL3026) is a highly specific antibody designed for research involving the CD44H protein, a cell surface molecule associated with cell adhesion and migration. This antibody is particularly useful in studies related to immunology, cell biology, and cancer research.The PE-Cyanine7 Anti-Rat CD44H Antibody (OX-49) is raised against rat samples and is validated for use in flow cytometry applications. It specifically binds to the CD44H protein, enabling precise detection and analysis in rat cell samples. This antibody is essential for understanding the role of CD44H in processes such as cell signaling, adhesion, and metastasis.CD44H is a crucial cell surface glycoprotein that plays a significant role in cell-cell interactions, cell adhesion, and migration.

It is involved in processes such as lymphocyte activation and homing, as well as tumor metastasis. By targeting CD44H with this antibody, researchers can gain valuable insights into these biological processes and potentially uncover new therapeutic targets for diseases such as cancer and inflammatory disorders.The PE-Cyanine7 Anti-Rat CD44H Antibody (OX-49) is a powerful tool for investigators looking to elucidate the intricate mechanisms by which CD44H influences cellular behavior and disease progression. Its high specificity and sensitivity make it an invaluable resource for cutting-edge research in the fields of immunology and oncology.

Product Title:PE/Cyanine7 Anti-Rat CD44H Antibody [OX-49]
SKU:AGEL3026
Size:25µg, 100µg
Clone No:OX-49
Synonyms:Pgp-1; H-CAM; CD44s;CD44H;
Host Species:Mouse
Reactivity:Rat
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:PE/Cyanine7 Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P26051
Gene ID:12505
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD44 is an 80-95 kD cell surface glycoprotein. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. It is up-regulated when T cells and B cells are activated. It was reported that CD44 is a valuable marker for memory T cells. CD44 is an adhesion molecule involved in leukocyte adhesion and homing to lymphoid organs. The OX-49 antibody reacts with CD44H (known as CD44s) expressed on most leukocytes, except for a subset of B lymphocytes. The epitope recognized by OX-49 antibody has been mapped to a region on both the standard, CD44s, and the splice variant, CD44v, isoforms of CD44. However it was reported that OX-49 antibody cannot detect the CD44V isoform, possibly due to conformational changes in the epitope.

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