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PE/Cyanine7 Anti-Rat CD44H Antibody [OX-49] (AGEL3025)

SKU:
AGEL3025
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Rat
Host Species:
Mouse
Isotype:
Mouse IgG2a, κ
Clone:
OX-49
Conjugation:
PE/Cyanine7
€169 - €409
Frequently bought together:

Description

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PE/Cyanine7 Anti-Rat CD44H Antibody [OX-49]

The PE-Cyanine7 Anti-Rat CD44H Antibody (OX-49) is a vital tool for researchers exploring the function of CD44H, a cell surface glycoprotein known to play a key role in cell adhesion and migration. This antibody, specifically designed for use with rat samples, is highly specific and provides accurate detection and analysis of CD44H expression in various cell types.CD44H, a variant of the CD44 molecule, is involved in processes such as cell-cell interactions, lymphocyte activation, and tumor metastasis, making it a crucial target for investigation in fields like immunology and cancer research. The PE-Cyanine7 Anti-Rat CD44H Antibody (OX-49) enables scientists to study the expression pattern and localization of CD44H in a reliable and reproducible manner, contributing to a better understanding of its role in physiological and pathological processes.

By utilizing this antibody, researchers can deepen their insights into the functions of CD44H and its implications in health and disease. With its high specificity and sensitivity, the PE-Cyanine7 Anti-Rat CD44H Antibody (OX-49) is a valuable tool for furthering scientific knowledge and uncovering new therapeutic opportunities in various research areas.

Product Title:PE/Cyanine7 Anti-Rat CD44H Antibody [OX-49]
SKU:AGEL3025
Size:50 Tests, 100 Tests, 200 Tests
Clone No:OX-49
Synonyms:Pgp-1; H-CAM; CD44s;CD44H;
Host Species:Mouse
Reactivity:Rat
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:PE/Cyanine7 Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P26051
Gene ID:12505
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD44 is an 80-95 kD cell surface glycoprotein. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. It is up-regulated when T cells and B cells are activated. It was reported that CD44 is a valuable marker for memory T cells. CD44 is an adhesion molecule involved in leukocyte adhesion and homing to lymphoid organs. The OX-49 antibody reacts with CD44H (known as CD44s) expressed on most leukocytes, except for a subset of B lymphocytes. The epitope recognized by OX-49 antibody has been mapped to a region on both the standard, CD44s, and the splice variant, CD44v, isoforms of CD44. However it was reported that OX-49 antibody cannot detect the CD44V isoform, possibly due to conformational changes in the epitope.

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