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PE/Cyanine7 Anti-Mouse Ly6A/E (Sca-1) Antibody [D7] (AGEL2355)

SKU:
AGEL2355
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, κ
Clone:
D7
Conjugation:
PE/Cyanine7
$239 - $647
Frequently bought together:

Description

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PE/Cyanine7 Anti-Mouse Ly6A/E (Sca-1) Antibody [D7]

The PE-Cyanine7 Anti-Mouse Ly6A/E (Sca-1) Antibody (D7, AGEL2355) offered by AssayGenie is a potent tool for researchers studying mouse Ly6A/E (Sca-1), a cell surface marker commonly used to identify and isolate hematopoietic stem cells and other progenitor populations. This antibody, developed specifically for mouse samples, exhibits high specificity and sensitivity, making it ideal for flow cytometry and immunofluorescence applications. Ly6A/E (Sca-1) is a key marker in stem cell and developmental biology, assisting researchers in distinguishing between different cell populations and understanding their roles in tissue regeneration and disease processes.

By accurately detecting and quantifying Ly6A/E (Sca-1)-positive cells, this antibody facilitates detailed analyses of cellular dynamics, differentiation, and function, ultimately contributing to advancements in regenerative medicine, cancer research, and immunology. For scientists investigating the intricate mechanisms underlying stem cell biology, tissue regeneration, or immune system function in mouse models, the PE-Cyanine7 Anti-Mouse Ly6A/E (Sca-1) Antibody (D7, AGEL2355) from AssayGenie is a reliable and indispensable tool for their experimental pursuits.

Product Title:PE/Cyanine7 Anti-Mouse Ly6A/E (Sca-1) Antibody [D7]
SKU:AGEL2355
Size:25µg, 100µg
Clone No:D7
Synonyms:Ly6a;Ly6;Ly-6A.2/Ly-6E.1;SCA-1;TAP;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine7 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P05533
Gene ID:110454
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.

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