The PE-Cyanine7 Anti-Mouse IL-17A Antibody (17F3, AGEL3128) from AssayGenie is a highly specific and reliable tool for detecting and studying Interleukin-17A (IL-17A) in mouse samples. IL-17A is a cytokine that plays a key role in inflammatory responses and autoimmune diseases, making it a critical target for research in immunology and related fields. This antibody, developed for use in flow cytometry, immunofluorescence, and other applications, offers exceptional sensitivity and accuracy in detecting IL-17A in mouse cells and tissues.The PE-Cyanine7 Anti-Mouse IL-17A Antibody binds specifically to IL-17A, enabling precise detection and quantification in various experimental settings. Its high reactivity and specificity make it a valuable tool for investigating the role of IL-17A in immune responses, inflammation, and disease pathology.
Researchers studying autoimmune disorders, inflammatory conditions, and the immune system in general will find this antibody essential for their experiments.By using the PE-Cyanine7 Anti-Mouse IL-17A Antibody (17F3, AGEL3128), researchers can gain valuable insights into the function and regulation of IL-17A in mouse models, advancing our understanding of immune responses and potential therapeutic targets. Trust AssayGenie's high-quality antibody to deliver reliable and reproducible results, facilitating impactful research in immunology and beyond.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
Q62386
Gene ID:
16171
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
The 17F3 monoclonal antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and chronic inflammation by inducing cytokine and chemokine production, neutrophil influx, and the production of antibacterial peptides but it is also an inflammatory mediator in the development of autoimmune diseases including rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis. The 17F3 antibody has been shown to neutralize IL-41A in vivo.