The PE-Cyanine7 Anti-Mouse/Human CD11b Antibody (clone M1/70) from Assay Genie is a crucial tool for immunologists and researchers studying immune responses and cell populations. This antibody specifically targets the CD11b protein, a marker expressed on the surfaces of mouse and human cells, including monocytes, macrophages, and granulocytes.The PE-Cyanine7 fluorophore conjugated to this antibody offers bright and stable fluorescence for multi-color flow cytometry experiments, allowing for precise identification and analysis of CD11b-positive cells. With high specificity and sensitivity, researchers can confidently distinguish between different immune cell subpopulations and monitor changes in CD11b expression in various biological contexts.
Whether investigating inflammatory processes, immune cell recruitment, or myeloid cell activation, the PE-Cyanine7 Anti-Mouse/Human CD11b Antibody provides reliable results and valuable insights into the complex interactions of the immune system. Trust in Assay Genie's expertise and quality products to enhance your research in immunology, inflammation, and beyond.
Integrin alpha-M;Itgam;CD11 antigen-like family member B;CR-3 alpha chain;Leukocyte adhesion receptor MO1;CD11b;
Host Species:
Rat
Reactivity:
Human;Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
PE/Cyanine7 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
PE/Cyanine 7
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P05555 P11215
Gene ID:
16409,3684
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.