The PE-Cyanine7 Anti-Mouse H-2 Antibody (M1/42) available at assaygenie.com is a valuable tool for research involving mouse immune responses. This antibody, specifically designed for use in flow cytometry applications, allows for the identification and analysis of H-2 molecules on mouse cells.The H-2 complex is a group of genes that encode cell surface molecules important for immune recognition and self/non-self-discrimination in mice. The PE-Cyanine7 Anti-Mouse H-2 Antibody (M1/42) binds specifically to these molecules, enabling researchers to study antigen presentation, T-cell activation, and immune responses in various experimental settings.
With its high specificity and sensitivity, this antibody is an essential reagent for studies in immunology, transplantation, and infectious disease research. By accurately detecting H-2 expression on mouse cells, researchers can gain insights into immune system function, host-pathogen interactions, and immune-mediated diseases. Trust the PE-Cyanine7 Anti-Mouse H-2 Antibody (M1/42) for reliable and reproducible results in your research.
Product Title:
PE/Cyanine7 Anti-Mouse H-2 Antibody [M1/42]
SKU:
AGEL3157
Size:
25µg, 100µg
Clone No:
M1/42
Synonyms:
Mouse major histocompatibility complex (MHC) H-2; MHC I;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
PE/Cyanine7 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
PE/Cyanine 7
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Gene ID:
111364
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
The M1/42 antibody reacts with the H-2 MHC class I alloantigens expressed on nucleated cells from mice of the a, b, d, j, k, s, and u haplotypes (Stallcup, KC et al, 1981). MHC class I is involved in antigen presentation to T cells expressing CD3/TCR and CD8 proteins.