The PE-Cyanine7 Anti-Mouse CD73 Antibody (TY/23) is a potent tool designed for researchers studying CD73, a key cell surface enzyme involved in immune regulation and cancer progression. This antibody, optimized for use in flow cytometry applications, offers high specificity and sensitivity when detecting CD73 expression in mouse samples. By binding to the CD73 protein, researchers can accurately analyze and quantify CD73 levels in different cell populations, providing valuable insights into immune responses and tumor microenvironments.CD73, also known as ecto-5'-nucleotidase, plays a crucial role in modulating immune responses by converting extracellular adenosine monophosphate into adenosine. This process regulates inflammation, immune cell function, and tissue repair, making CD73 a promising target for immunotherapy and cancer treatment research.
Understanding the expression and activity of CD73 in the context of immune regulation and tumor immunity is essential for developing novel therapeutic strategies that leverage its biological functions.Ideal for immunology, oncology, and drug development studies, the PE-Cyanine7 Anti-Mouse CD73 Antibody (TY/23) offers reliable performance and reproducibility, allowing researchers to explore the complex interplay between CD73 expression, immune modulation, and tumor progression. With its validated specificity and robust performance, this antibody is a valuable resource for scientists investigating the role of CD73 in health and disease.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
Q61503
Gene ID:
23959
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD73 (ecto-5`-nucleotidase) is a 69 kD GPI-anchored surface protein. In mice, expression of CD73 in bone marrow is restricted to CD11b+ myeloid cells. In spleen, it is largely expressed on T cells.