The PE-Cyanine7 Anti-Mouse CD64 Antibody (X54-5/7.1) is a vital tool for researchers studying immune responses in mice. This antibody, specifically designed for detecting the CD64 protein on mouse cells, provides a reliable means of analyzing immune cell activation and function. With its high specificity and sensitivity, this antibody is ideal for flow cytometry and immunofluorescence applications, allowing for precise identification and quantification of CD64-expressing cells in various samples.CD64, also known as Fc-gamma receptor I, is a crucial component of the immune system, playing a key role in the recognition and phagocytosis of pathogens.
Its expression on different immune cell types can provide valuable insights into immune responses during infection, inflammation, and autoimmune diseases. By targeting CD64 with this antibody, researchers can delve deeper into the mechanisms underlying immune activation and regulation in mouse models, paving the way for advancements in immunotherapy and vaccine development.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P26151
Gene ID:
14129
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcRI. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and mast cells. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).