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PE/Cyanine7 Anti-Mouse CD51 Antibody [RMV-7] (AGEL2765)

SKU:
AGEL2765
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG1, κ
Clone:
RMV-7
Conjugation:
PE/Cyanine7
$275 - $647
Frequently bought together:

Description

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PE/Cyanine7 Anti-Mouse CD51 Antibody [RMV-7]

The PE-Cyanine7 Anti-Mouse CD51 Antibody (RMV-7) is a high-quality research tool designed for the detection of CD51, a cell surface adhesion molecule involved in cell migration and signaling. This antibody is specifically engineered for use in flow cytometry and immunofluorescence experiments, enabling precise identification and analysis of CD51-expressing cells in mouse samples.CD51, also known as integrin alpha V, plays a key role in cellular adhesion and migration processes, making it a significant target for investigation in the fields of cell biology, immunology, and cancer research. By accurately detecting and quantifying CD51 expression, researchers can gain insights into its function in various biological processes and diseases, ultimately advancing our understanding of cell behavior and potential therapeutic targets.

The PE-Cyanine7 Anti-Mouse CD51 Antibody (RMV-7) offers excellent specificity and sensitivity, providing reliable results for studies focusing on integrin alpha V biology and related pathways. With its validated performance and compatibility with common research techniques, this antibody is a valuable asset for scientists seeking to explore the intricate mechanisms underlying cellular interactions and disease progression.

Product Title:PE/Cyanine7 Anti-Mouse CD51 Antibody [RMV-7]
SKU:AGEL2765
Size:25µg, 100µg
Clone No:RMV-7
Synonyms:Integrin alpha-V;αV integrin;Vitronectin Receptor;Integrin αV chain;ITGAV;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG1, κ
Isotype Control:PE/Cyanine7 Rat IgG1, κ Isotype Control[HRPN]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P43406
Gene ID:16410
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD51 is a 140 kD protein, also known as αV integrin, vitronectin receptor, and integrin αV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins β1, β3, β5 or β6; these complexes then act as receptors for multiple extracellular matrix proteins (ECM). The αvintegrin heterodimers have varied functions in development, stimulation/activation and homeostasis. The primary ligands for CD51 complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity.

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