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PE/Cyanine7 Anti-Mouse CD51 Antibody [RMV-7] (AGEL2763)

SKU:
AGEL2763
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG1, κ
Clone:
RMV-7
Conjugation:
PE/Cyanine7
€259 - €609
Frequently bought together:

Description

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PE/Cyanine7 Anti-Mouse CD51 Antibody [RMV-7]

The PE-Cyanine7 Anti-Mouse CD51 Antibody (RMV-7) is a highly specific and sensitive tool designed for researchers studying CD51, a key cell surface marker associated with cell adhesion and migration. This antibody, optimized for flow cytometry applications, is rigorously validated for use in mouse samples, providing reliable and accurate results for experimental analysis.CD51, also known as integrin alpha V, is a crucial component of integrin-mediated signaling pathways involved in cell proliferation, differentiation, and tissue remodeling. Its dynamic expression pattern and functional role in cell-cell and cell-matrix interactions make it a promising target for investigations in various fields such as cancer biology, developmental biology, and stem cell research.

The PE-Cyanine7 Anti-Mouse CD51 Antibody enables precise detection and quantification of CD51 expression in different cell populations, offering valuable insights into the mechanisms underlying cell behavior and tissue dynamics.Researchers aiming to elucidate the complex functions of CD51 and its contribution to physiological and pathological processes will benefit from the specificity and versatility of the PE-Cyanine7 Anti-Mouse CD51 Antibody (RMV-7). With its superior performance in flow cytometry analyses, this antibody empowers detailed studies on the role of CD51 in various cellular contexts, paving the way for novel discoveries and therapeutic advancements in the realms of cancer research, tissue regeneration, and beyond.

Product Title:PE/Cyanine7 Anti-Mouse CD51 Antibody [RMV-7]
SKU:AGEL2763
Size:50 Tests, 100 Tests, 200 Tests
Clone No:RMV-7
Synonyms:Integrin alpha-V;αV integrin;Vitronectin Receptor;Integrin αV chain;ITGAV;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG1, κ
Isotype Control:PE/Cyanine7 Rat IgG1, κ Isotype Control[HRPN]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P43406
Gene ID:16410
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD51 is a 140 kD protein, also known as αV integrin, vitronectin receptor, and integrin αV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins β1, β3, β5 or β6; these complexes then act as receptors for multiple extracellular matrix proteins (ECM). The αvintegrin heterodimers have varied functions in development, stimulation/activation and homeostasis. The primary ligands for CD51 complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity.

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