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PE/Cyanine7 Anti-Mouse CD41 Antibody [MWReg30] (AGEL2308)

SKU:
AGEL2308
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG1, κ
Clone:
MWReg30
Conjugation:
PE/Cyanine7
€199 - €539
Frequently bought together:

Description

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PE/Cyanine7 Anti-Mouse CD41 Antibody [MWReg30]

The PE-Cyanine7 Anti-Mouse CD41 Antibody (MWReg30) is a crucial tool for studying platelet biology and function in research settings. This antibody recognizes the CD41 antigen, also known as integrin alpha IIb, which is a well-established marker for identifying platelets in murine samples. By specifically binding to CD41, this antibody enables precise detection and analysis of platelet populations in various experimental contexts.In platelet biology, CD41 is essential for platelet adhesion and aggregation, playing a central role in hemostasis and thrombosis. The PE-Cyanine7 Anti-Mouse CD41 Antibody provides researchers with a reliable method for investigating platelet activation, platelet-related disorders, and the role of platelets in different physiological and pathological processes.

Its compatibility with flow cytometry applications makes it a versatile tool for high-throughput analysis of platelet function and dynamics.With its high specificity and sensitivity, the PE-Cyanine7 Anti-Mouse CD41 Antibody is a valuable asset for studies focused on understanding the molecular mechanisms underlying platelet physiology and pathology. By using this antibody, researchers can gain insights into platelet behavior in various disease states, paving the way for potential therapeutic interventions targeting platelet function.

Product Title:PE/Cyanine7 Anti-Mouse CD41 Antibody [MWReg30]
SKU:AGEL2308
Size:25µg, 100µg
Clone No:MWReg30
Synonyms:Itga2b;GPalpha Iib;CD41;GPIIb;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG1, κ
Isotype Control:PE/Cyanine7 Rat IgG1, κ Isotype Control[HRPN]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q9QUM0
Gene ID:16399
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD41, also known as integrin α2b and GPIIb, is a transmembrane glycoprotein that is expressed by platelets and megakaryocytes. It was reported that CD41 is also expressed on hematopoietic progenitors. CD41 associates with CD61 (integrin β3) to form complexes that interact with fibrinogen, fibronectin, von Willebrand factor, and thrombin. CD41 is required for platelet adhesion and aggregation. Defect of CD41 leads to disorders of coagulation.

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