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PE/Cyanine7 Anti-Mouse CD41 Antibody [MWReg30] (AGEL2307)

SKU:
AGEL2307
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG1, κ
Clone:
MWReg30
Conjugation:
PE/Cyanine7
€159 - €389
Frequently bought together:

Description

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PE/Cyanine7 Anti-Mouse CD41 Antibody [MWReg30]

The PE-Cyanine7 Anti-Mouse CD41 Antibody (MWReg30) is a vital tool for researchers studying platelet biology and related processes. This antibody, derived from a hybridoma cell line, specifically targets the CD41 antigen found on the surface of mouse platelets. With its fluorophore conjugation, this antibody is ideal for flow cytometry applications, allowing for the precise identification and quantification of CD41-expressing cells in various experimental settings.The CD41 antigen, also known as integrin alpha IIb, plays a crucial role in platelet aggregation and clot formation, making it a key marker for studying thrombosis, hemostasis, and related pathways in murine models.

By utilizing the PE-Cyanine7 Anti-Mouse CD41 Antibody, researchers can track platelet dynamics, investigate platelet function in disease models, and assess the efficacy of anti-platelet therapies.With its high specificity and sensitivity, this antibody offers reliable results and reproducible data, ensuring accurate interpretation of experimental outcomes. Researchers in the fields of hematology, vascular biology, and immunology will find the PE-Cyanine7 Anti-Mouse CD41 Antibody to be an indispensable tool for advancing their understanding of platelet biology and its implications in health and disease.

Product Title:PE/Cyanine7 Anti-Mouse CD41 Antibody [MWReg30]
SKU:AGEL2307
Size:50 Tests, 100 Tests, 200 Tests
Clone No:MWReg30
Synonyms:Itga2b;GPalpha Iib;CD41;GPIIb;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG1, κ
Isotype Control:PE/Cyanine7 Rat IgG1, κ Isotype Control[HRPN]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q9QUM0
Gene ID:16399
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD41, also known as integrin α2b and GPIIb, is a transmembrane glycoprotein that is expressed by platelets and megakaryocytes. It was reported that CD41 is also expressed on hematopoietic progenitors. CD41 associates with CD61 (integrin β3) to form complexes that interact with fibrinogen, fibronectin, von Willebrand factor, and thrombin. CD41 is required for platelet adhesion and aggregation. Defect of CD41 leads to disorders of coagulation.

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