The PE-Cyanine7 Anti-Mouse CD4 Antibody (Clone RM4-5) is a powerful tool for researching CD4, a critical cell surface marker involved in immune responses and T cell development. This antibody, specifically designed for use in flow cytometry and immunofluorescence applications, is highly specific to mouse CD4 protein and allows for precise detection and analysis in various experimental settings.CD4, also known as T4 antigen, is a glycoprotein expressed on the surface of helper T cells, which are instrumental in coordinating the immune response against pathogens and foreign substances. The PE-Cyanine7 Anti-Mouse CD4 Antibody enables researchers to accurately identify and characterize CD4-positive cells, facilitating studies related to immunology, infectious diseases, autoimmunity, and transplantation.
By targeting CD4 and providing reliable detection capabilities, this antibody supports investigations into immune cell populations, immune system function, and the development of therapeutic strategies targeting CD4-positive cells. With its high specificity and sensitivity, the PE-Cyanine7 Anti-Mouse CD4 Antibody (Clone RM4-5) is an essential reagent for scientists seeking to advance their understanding of immune responses and T cell-mediated immunity in experimental models.
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P06332
Gene ID:
12504
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4 is a 55 kD protein also known as L3T4 or T4. It is a member of the Ig superfamily, primarily expressed on most thymocytes and a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a co-receptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosine kinase lck.