The PE-Cyanine7 Anti-Mouse CD326 Antibody (G8.8) is a potent tool for researchers studying CD326, a cell surface marker also known as EpCAM involved in cell adhesion and signaling pathways. This antibody, specifically designed for mouse samples, is raised in host animals to ensure high reactivity and specificity. Validated for use in flow cytometry applications, it enables precise detection and quantification of CD326 expression in various cell populations, making it well-suited for immunology and stem cell research.CD326, a transmembrane glycoprotein, is recognized for its role in epithelial cell adhesion and differentiation, with implications in various physiological and pathological processes.
Its involvement in cellular functions and signaling cascades positions it as a key target for investigating developmental biology, cancer progression, and tissue regeneration. Unraveling the mechanisms governed by CD326 is crucial for advancing knowledge in these areas and developing innovative therapeutic strategies that leverage its biological functions.
Product Title:
PE/Cyanine7 Anti-Mouse CD326 Antibody [G8.8]
SKU:
AGEL2751
Size:
25µg, 100µg
Clone No:
G8.8
Synonyms:
Tacstd1;EpCAM;Ep-CAM;Megp314;EGP314;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
PE/Cyanine7 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
PE/Cyanine 7
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
Q99JW5
Gene ID:
17075
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
EpCAM (CD326) mediates calcium-independent homophilic cell to cell adhesion. It may also function as a growth factor receptor. It is thought to be involved in maintaining cells in position during proliferation. Expression of EpCAM seems to correlate inversely with the level of E-cadherin (CD324). EpCAM is considered important in tumor biology.