The PE-Cyanine7 Anti-Mouse CD23 Antibody (B3B4) is a versatile tool designed for researchers studying the CD23 protein in mouse models. This antibody, produced specifically for detecting CD23 expression, is highly sensitive and reliable in flow cytometry applications. With its PE-Cyanine7 conjugation, it offers bright and stable fluorescence signals, enabling accurate identification and analysis of CD23-expressing cells in flow cytometry experiments.CD23, also known as FcεRII, is a key receptor involved in regulating IgE-mediated immune responses and B cell activation. Understanding the expression and function of CD23 is essential in unraveling its role in allergic reactions, immune regulation, and antibody production.
By utilizing the PE-Cyanine7 Anti-Mouse CD23 Antibody (B3B4), researchers can investigate the dynamics of CD23 expression in different immune cell populations, providing valuable insights into immune system modulation and potential therapeutic targets for immune-related disorders.This antibody's specificity and performance make it a valuable tool for immunologists, cell biologists, and researchers working in the fields of immunology, allergy, and autoimmunity. Its application in flow cytometry studies facilitates detailed investigations into CD23 biology, paving the way for advancements in understanding immune responses and developing targeted therapies for immune-related diseases.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P20693
Gene ID:
14128
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD23 is a 45 kD protein also known as low affinity IgE Fc receptor, FcεRII, BLAST-2, Ly-42, or B6. It is a member of the Ig family, expressed on conventional B (but not B-1) cells and follicular dendritic cells. CD23 responds to high levels of IgE by downregulating IgE secretion.