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PE/Cyanine7 Anti-Mouse CD200 Antibody [OX-90] (AGEL2760)

SKU:
AGEL2760
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, κ
Clone:
OX-90
Conjugation:
PE/Cyanine7
$347 - $851
Frequently bought together:

Description

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PE/Cyanine7 Anti-Mouse CD200 Antibody [OX-90]

The PE-Cyanine7 Anti-Mouse CD200 Antibody (Clone OX-90) is a vital tool for researchers studying immune regulation and cell surface molecules in mice. This antibody, specific to the CD200 protein, is ideal for flow cytometry applications, enabling precise detection and analysis of CD200 expression in various cell types.CD200 is a cell surface glycoprotein known for its immunomodulatory properties, playing a key role in the regulation of immune responses and inflammation. Its interaction with the CD200 receptor is essential for maintaining immune tolerance and preventing excessive immune activation. The PE-Cyanine7 Anti-Mouse CD200 Antibody provides researchers with a reliable means to investigate the function and expression of CD200 in immune cells, offering valuable insights into immune regulation mechanisms.

Utilizing this antibody in research can enhance our understanding of immune homeostasis and the potential therapeutic targets for immune-related disorders such as autoimmune diseases, allergies, and inflammatory conditions. By unraveling the intricate pathways controlled by CD200, researchers can pave the way for the development of novel treatments and interventions aimed at modulating immune responses for improved health outcomes.

Product Title:PE/Cyanine7 Anti-Mouse CD200 Antibody [OX-90]
SKU:AGEL2760
Size:50 Tests, 100 Tests, 200 Tests
Clone No:OX-90
Synonyms:OX-2 membrane glycoprotein;OX-2; MRC;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine7 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:O54901
Gene ID:4345
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD200 (OX-2 antigen) is a type-1 membrane glycoprotein containing two extracellular Ig-like domains. CD200 a highly conserved type I membrane glycoprotein that is expressed on a variety of cell types including thymocytes, some T cells, endothelial and follicular dendritc cells, B cells, and brain tissue (neurons); but not on NK cells, granulocytes, monocytes, or macrophages. CD200 costimulates T cell proliferation. It may regulate myeloid cell activity in a variety of tissues. CD200 is the ligand for CD200 receptor (CD200R). The CD200 Receptor is restricted to myeloid cells, and it is believed that its engagement with CD200 results in inhibition and/or downregulation of myeloid cell activity. Blocking of CD200/CD200R interactions decreases myeloid cell inhibitory thresholds which results in enhanced immune activation.

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