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PE/Cyanine7 Anti-Mouse CD18 Antibody [M18/2] (AGEL2745)

SKU:
AGEL2745
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, κ
Clone:
M18/2
Conjugation:
PE/Cyanine7
€199 - €459
Frequently bought together:

Description

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PE/Cyanine7 Anti-Mouse CD18 Antibody [M18/2]

The PE-Cyanine7 Anti-Mouse CD18 Antibody (M18/2) offered by AssayGenie (AGEL2745) is a powerful tool for researchers studying mouse immune responses and cell adhesion mechanisms. This antibody, specifically designed for flow cytometry applications, targets the CD18 protein which is crucial for leukocyte adhesion and transendothelial migration.Mouse CD18, also known as Integrin beta-2, plays a vital role in the immune system by facilitating cell-cell interactions and migration to sites of inflammation. The PE-Cyanine7 Anti-Mouse CD18 Antibody (M18/2) enables precise detection and analysis of CD18 expression on mouse cells, providing valuable insights into immune cell functions and inflammatory processes.

With its high specificity and sensitivity, this antibody is a valuable asset for immunologists, hematologists, and researchers studying immune cell trafficking, inflammation, and autoimmune diseases in mouse models. By targeting CD18, researchers can unravel the complexities of immune responses and develop targeted therapies for conditions where immune cell migration and adhesion play a critical role.

Product Title:PE/Cyanine7 Anti-Mouse CD18 Antibody [M18/2]
SKU:AGEL2745
Size:25µg, 100µg
Clone No:M18/2
Synonyms:Integrin beta-2;Itgb2;Cell surface adhesion glycoproteins LFA-1/CR3/p150+95 subunit beta;Complement receptor C3 subunit beta;CD18;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine7 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P11835
Gene ID:16414
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD18 is a 95 kD protein, also known as integrin β2 subunit. It is expressed on all leukocytes. CD18, in association with integrin α chain CD11a, CD11b, and CD11c forms LFA-1, Mac-1, and αXβ2, respectively, and plays an important role in leukocytes adhesion. The CD18 integrin complexes bind ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50), iC3b, and fibrinogen.

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