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PE/Cyanine7 Anti-Mouse CD117 Antibody [2B8] (AGEL3051)

SKU:
AGEL3051
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2b, κ
Clone:
2B8
Conjugation:
PE/Cyanine7
$275 - $647
Frequently bought together:

Description

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PE/Cyanine7 Anti-Mouse CD117 Antibody [2B8]

The PE-Cyanine7 Anti-Mouse CD117 Antibody (2B8, AGL3051) offered by AssayGenie is a versatile tool for researchers studying mouse CD117, a protein known for its role in hematopoiesis and mast cell development. This antibody, produced against mouse CD117, demonstrates high specificity and sensitivity in various experimental applications.CD117, also known as c-Kit or stem cell factor receptor, is a transmembrane tyrosine kinase receptor involved in cell proliferation, differentiation, and migration. It plays a crucial role in hematopoiesis, melanogenesis, and gametogenesis, making it a key target in stem cell and cancer research.The PE-Cyanine7 Anti-Mouse CD117 Antibody (2B8, AGL3051) is optimized for flow cytometry analysis, allowing for precise identification and quantification of CD117-expressing cells in complex biological samples.

Its bright fluorescent signal and low background noise make it a reliable tool for studying the expression and distribution of CD117 in diverse cell populations.With its high specificity and exceptional performance in flow cytometry, the PE-Cyanine7 Anti-Mouse CD117 Antibody (2B8, AGL3051) from AssayGenie is an essential reagent for researchers investigating the functional roles of CD117 in hematopoiesis, cancer biology, and cell signaling pathways. Unlock the potential of your research with this reliable antibody designed to support breakthrough discoveries in the field of immunology and molecular biology.

Product Title:PE/Cyanine7 Anti-Mouse CD117 Antibody [2B8]
SKU:AGEL3051
Size:50 Tests, 100 Tests, 200 Tests
Clone No:2B8
Synonyms:Mast/stem cell growth factor receptor Kit;Kit;SCFR;Proto-oncogene c-Kit;Tyrosine-protein kinase Kit;CD117;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE/Cyanine7 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P05532
Gene ID:16590
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.

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