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PE/Cyanine7 Anti-Mouse CD107a Antibody [1D4B] (AGEL3290)

SKU:
AGEL3290
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
ICFCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, k
Clone:
1D4B
Conjugation:
PE/Cyanine7
€259 - €609
Frequently bought together:

Description

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PE/Cyanine7 Anti-Mouse CD107a Antibody [1D4B]

The PE-Cyanine7 Anti-Mouse CD107a Antibody (1D4B) offered by AssayGenie is a high-quality reagent designed for the detection and analysis of CD107a, a crucial marker of degranulation in immune cells, especially cytotoxic T cells and natural killer cells. This antibody is specifically engineered for use in flow cytometry applications and is optimized to provide accurate and reliable results in mouse samples.CD107a, also known as Lysosomal-associated membrane protein-1 (LAMP-1), is a key player in the exocytosis of cytotoxic granules containing perforin and granzymes. By targeting CD107a, researchers can investigate and quantify the cytotoxic activity of immune cells, shedding light on their functional capacity in response to pathogens or tumor cells.

This antibody allows for precise identification and quantification of CD107a-expressing cells, aiding in the study of immune responses, infectious diseases, and cancer immunotherapy.Whether you are studying immune cell function, investigating anti-tumor immunity, or exploring immune surveillance mechanisms, the PE-Cyanine7 Anti-Mouse CD107a Antibody (1D4B) from AssayGenie provides a reliable tool to advance your research and deepen our understanding of immune responses in health and disease.

Product Title:PE/Cyanine7 Anti-Mouse CD107a Antibody [1D4B]
SKU:AGEL3290
Size:50 Tests, 100 Tests, 200 Tests
Clone No:1D4B
Synonyms:LAMP-1;Lysosome-associated membrane glycoprotein 1; lysosomal membrane glycoprotein 1; CD107 antigen-like family member A; lysosome-associated membrane protein 1;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine7 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P11438
Gene ID:16783
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:The 1D4B antibody recognizes CD107a which is also known as, Lysosome-Associated Membrane Protein 1 (LAMP-1). CD107a is one of the two major glycoproteins in lysosome membranes that provide useful markers to distinguish lysosomes from other organelles. CD107a may play a role in the lysosomal degradation of certain molecules. Mouse CD107a is a type I transmembrane glycoprotein. It consists of a 40-kDa core protein which is heavily glycosylated to form heterogeneous mature glycoprotein of 110-140 kDa. It is principally expressed in epithelial cells and macrophages in a variety of organs. Following activation, CD107a is relocated to the surface of some lymphocytes, macrophages, epithelial cells, endothelial cells, platelets, and tumor cells. Cell-surface CD107a may participate in intercellular adhesion and adhesion to the extracellular matrix. Cell surface CD107a expression can serve as a useful marker for cytotoxic NK and CD8+ T cells, as well as, some malignant tumor cells.

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