The PE-Cyanine7 Anti-Human CD83 Antibody (HB15e) offered by AssayGenie is a robust tool for research involving CD83, a surface marker found on dendritic cells and B cells that plays a vital role in immune response regulation. This monoclonal antibody specifically recognizes the human CD83 protein and is suitable for flow cytometry applications. Its high sensitivity and specificity make it an ideal choice for studying immune cell populations and cell signaling pathways associated with dendritic cell maturation and activation.CD83 is a key molecule in the activation and maturation of dendritic cells, crucial for initiating and regulating immune responses.
Research into CD83 expression and function is essential for understanding how dendritic cells influence adaptive immunity, making this antibody invaluable for investigations in immunology, vaccine development, and transplantation studies. With its superior performance and reliability, the PE-Cyanine7 Anti-Human CD83 Antibody (HB15e) is a valuable tool for researchers exploring immune cell dynamics and immune system function in health and disease.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
Q01151
Gene ID:
9315
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD83 is a 43 kD single chain type I glycoprotein also known as HB15. A member of the immunoglobulin superfamily, CD83 is expressed on a subset of dendritic cells, Langerhans cells, and weakly on activated lymphocytes. Although CD83 is thought to play a role in antigen presentation and/or lymphocyte activation, the precise function of this protein is unknown. CD83 is considered to be a useful marker for mature dendritic cells.