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PE/Cyanine7 Anti-Human CD80 Antibody [2D10] (AGEL2759)

SKU:
AGEL2759
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, κ
Clone:
2D10
Conjugation:
PE/Cyanine7
€239 - €769
Frequently bought together:

Description

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PE/Cyanine7 Anti-Human CD80 Antibody [2D10]

The PE-Cyanine7 Anti-Human CD80 Antibody (2D10) offered by Assay Genie is a highly specific and reliable tool for researchers studying CD80, a crucial co-stimulatory protein involved in T cell activation and immune response regulation. This monoclonal antibody, optimized for flow cytometry applications, exhibits exceptional reactivity with human CD80 samples, enabling precise and accurate detection in various cell populations.CD80, also known as B7-1, is a key ligand for CD28 and CTLA-4 receptors on T cells, mediating essential signaling pathways essential for T cell activation, differentiation, and tolerance induction. The PE-Cyanine7 Anti-Human CD80 Antibody (2D10) allows for the visualization and quantification of CD80 expression levels on immune cells, making it an invaluable tool for studies focused on immunology, autoimmunity, transplantation, and infectious diseases.

This antibody's high specificity and sensitivity make it ideal for exploring the role of CD80 in immune responses, providing researchers with a versatile tool to investigate the complex interplay between CD80 and its interacting partners in health and disease. With its proven performance and broad applicability, the PE-Cyanine7 Anti-Human CD80 Antibody (2D10) from Assay Genie is a valuable asset for advancing our understanding of immune regulation mechanisms and identifying potential therapeutic targets for immunomodulatory interventions.

Product Title:PE/Cyanine7 Anti-Human CD80 Antibody [2D10]
SKU:AGEL2759
Size:20 Tests, 100 Tests, 200 Tests
Clone No:2D10
Synonyms:T-lymphocyte activation antigen CD80;B7-1; B7; BB1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE/Cyanine7 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P33681
Gene ID:941
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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