The PE/Cyanine7 Anti-Human CD66b Antibody (G10F5) offered by Assay Genie is a valuable tool for researchers studying CD66b, a cell surface antigen involved in immune cell interactions and functions. This antibody is specifically designed for flow cytometry applications, providing accurate detection and quantification of CD66b expression on human cells.CD66b, also known as CEACAM8, is a glycoprotein found on the surface of neutrophils and is involved in various immune responses, including adhesion and migration. By targeting CD66b with the G10F5 antibody, researchers can investigate the role of this antigen in inflammatory processes, infection responses, and immune cell signaling pathways.
The PE/Cyanine7 conjugate of this antibody offers enhanced sensitivity and signal strength for flow cytometry analysis, making it a reliable tool for identifying CD66b-positive cell populations within complex mixtures. With its high specificity and reproducibility, the PE/Cyanine7 Anti-Human CD66b Antibody (G10F5) is an essential reagent for immuno-oncology studies, infectious disease research, and immunology investigations focused on neutrophil biology.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P31997
Gene ID:
1088
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD66b is a 95-100 kD glycosylphosphatidylinositol (GPI)-linked protein also known as CD67, CGM6, and NCA-95. CD66b is a member of the immunoglobulin superfamily, carcinoembryonic antigen (CEA)-like subfamily. CD66b, expressed on granulocytes, has been reported to induce activation in neutrophils and to be involved in heterophilic adhesion with CD66c.