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PE/Cyanine7 Anti-Human CD326 Antibody [9C4] (AGEL2747)

SKU:
AGEL2747
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG2b, κ
Clone:
9C4
Conjugation:
PE/Cyanine7
€259 - €1,049
Frequently bought together:

Description

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PE/Cyanine7 Anti-Human CD326 Antibody [9C4]

The PE-Cyanine7 Anti-Human CD326 Antibody (9C4) offered by Assay Genie is a highly specific and reliable tool for research involving CD326, also known as EpCAM (Epithelial Cell Adhesion Molecule). This antibody, conjugated to PE-Cyanine7 for fluorescent detection, is optimized for use in flow cytometry and immunofluorescence applications. It exhibits strong reactivity with human CD326, enabling precise visualization and analysis of this cell surface marker in various cell types.CD326/Epcam is a well-studied glycoprotein that is often overexpressed in epithelial tumors, making it a pertinent target in cancer research and diagnostics. The 9C4 antibody facilitates the identification and characterization of CD326-positive cells, aiding in the understanding of tumor heterogeneity, metastasis, and epithelial-mesenchymal transition.

Its application extends to stem cell research, where CD326 serves as a marker for epithelial and cancer stem cells, offering valuable insights into cell differentiation and proliferation.Additionally, the PE-Cyanine7 Anti-Human CD326 Antibody (9C4) demonstrates minimal background staining and high signal-to-noise ratio, ensuring accurate and reproducible results in experimental settings. Researchers in the fields of oncology, stem cell biology, and molecular biology will benefit from the specificity, sensitivity, and versatility of this antibody in advancing their studies and contributing to scientific discoveries in the realm of cell biology and cancer research.

Product Title:PE/Cyanine7 Anti-Human CD326 Antibody [9C4]
SKU:AGEL2747
Size:20 Tests, 100 Tests, 200 Tests
Clone No:9C4
Synonyms:EpCAM;Ep-CAM;GA733-2;M1S2;M4S1;MIC18;TACSTD1; TROP1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2b, κ
Isotype Control:PE/Cyanine7 Mouse IgG2b, κ Isotype Control[MPC-11]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P16422
Gene ID:4072
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD326 is also known as Ep-CAM, tumor associated calcium signal transducer 1, epithelial cell surface antigen, epithelial glycoprotein 2, EGP2, adenocarcinoma associated antigen, and TROP1. CD326 is a type I transmembrane protein containing six disulfide bridges and one THYRO domain. This cell surface glycosylated 40 kD protein is highly expressed in bone marrow, colon, lung, and most normal epithelial cells and is expressed on carcinomas of gastrointestinal origin. Recently, it has been reported that CD326 expression occurs during the early steps of erythrogenesis. CD326 functions as a homotypic calcium-independent cell adhesion molecule and is believed to be involved in carcinogenesis by its ability to induce genes involved in cellular metabolism and proliferation. CD326 antigen is an immunotherapeutic target for the treatment of human carcinomas.

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