The PE-Cyanine7 Anti-Human CD31 Antibody (158-2B3) from Assay Genie is a powerful tool for researchers studying the CD31 molecule, a key player in vascular biology and inflammation. This antibody, optimized for use in flow cytometry applications, provides high specificity and sensitivity when detecting the CD31 protein on human samples.CD31, also known as platelet endothelial cell adhesion molecule-1 (PECAM-1), is a transmembrane glycoprotein involved in various biological processes, including leukocyte migration, thrombosis, and angiogenesis. Its role in mediating cell adhesion and signaling makes it a crucial target for understanding vascular function and immune responses.
The PE-Cyanine7 Anti-Human CD31 Antibody (158-2B3) allows for precise and accurate identification of CD31-expressing cells, facilitating detailed analysis of cellular interactions and signaling pathways. With its reliable performance and compatibility with flow cytometry techniques, this antibody is an essential tool for investigating the intricate functions of CD31 in vascular biology, inflammation, and related research areas.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P16284
Gene ID:
5175
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD31 is a 130-140 kD type I transmembrane glycoprotein also known as platelet endothelial cell adhesion molecule-1 (PECAM-1) or Endocam. It is expressed on monocytes, platelets, granulocytes, endothelial cells and lymphocyte subsets. CD31 has been reported to bind CD38 and be involved in wound healing, angiogenesis, and cellular migration in an inflammatory situation.