The PE-Cyanine7 Anti-Human CD19 Antibody (HI19A) is a cutting-edge research tool designed for the specific detection of CD19, a cell surface protein vital for B cell development and function. This antibody, synthesized for high reactivity and precision, is a valuable asset for immunology and oncology research applications.CD19, a key marker for B cells, plays a crucial role in immune response regulation and is often targeted in cancer therapy, particularly in B cell malignancies such as leukemia and lymphoma. The PE-Cyanine7 Anti-Human CD19 Antibody (HI19A) binds specifically to CD19, allowing for accurate identification and quantification in diverse experimental settings.
With its superior specificity and sensitivity, this antibody enables researchers to delve deep into the dynamics of B cell biology, immunotherapy development, and disease mechanisms. Whether investigating normal immune responses or exploring therapeutic interventions, the PE-Cyanine7 Anti-Human CD19 Antibody (HI19A) is an indispensable tool for advancing scientific understanding in the field of immunology.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P51677
Gene ID:
930
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD19 is a 95 kD type I transmembrane glycoprotein also known as B4. It is a member of the immunoglobulin superfamily expressed on B-cells (from pro-B to blastoid B cells, absent on plasma cells) and follicular dendritic cells. CD19 is involved in B cell development, activation, and differentiation. CD19 forms a complex with CD21 (CR2) and CD81 (TAPA-1), and functions as a BCR co-receptor.