The PE-Cyanine7 Anti-Human CD19 Antibody (CB19) offered by Assay Genie is a vital tool for research involving the CD19 antigen, a specific marker found on the surface of B cells. This antibody, optimized for fluorescent flow cytometry applications, is uniquely designed for detecting and analyzing CD19 expression in human samples with high sensitivity and specificity.CD19 is a key protein in the development and function of B cells, making it an important target for studying various aspects of the immune system, including B cell development, activation, and differentiation. The PE-Cyanine7 Anti-Human CD19 Antibody provides researchers with a reliable method for characterizing and quantifying CD19-expressing cells in diverse experimental contexts.
This antibody is particularly valuable for investigating diseases involving aberrant B cell populations, such as B cell leukemias and lymphomas, autoimmune disorders, and immunodeficiencies. By enabling precise identification and analysis of CD19-positive cells, this antibody contributes to a deeper understanding of B cell biology and aids in the development of potential diagnostic and therapeutic strategies for related conditions.Overall, the PE-Cyanine7 Anti-Human CD19 Antibody (CB19) from Assay Genie is a cutting-edge research tool that facilitates accurate and efficient exploration of CD19 expression and function in the context of immunological and hematological studies.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P15391
Gene ID:
930
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD19 is a 95 kD type I transmembrane glycoprotein also known as B4. It is a member of the immunoglobulin superfamily expressed on B-cells (from pro-B to blastoid B cells, absent on plasma cells) and follicular dendritic cells. CD19 is involved in B cell development, activation, and differentiation. CD19 forms a complex with CD21 (CR2) and CD81 (TAPA-1), and functions as a BCR co-receptor.