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PE/Cyanine7 Anti-Human CD183/CXCR3 Antibody [G025H7] (AGEL2286)

SKU:
AGEL2286
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, κ
Clone:
G025H7
Conjugation:
PE/Cyanine7
€279 - €939

Description

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PE/Cyanine7 Anti-Human CD183/CXCR3 Antibody [G025H7]

The PE-Cyanine7 Anti-Human CD183 (CXCR3) Antibody (G025H7) is a powerful tool for studying the CXCR3 protein, a chemokine receptor involved in immune responses, inflammation, and cancer progression. This antibody is specially designed for detection and analysis of human samples, offering high reactivity and specificity in flow cytometry and immunofluorescence applications.CXCR3 is a key receptor for chemokines involved in directing immune cell migration to sites of inflammation and injury. By targeting CXCR3, researchers can explore its role in various cellular processes, including immune cell recruitment, activation, and function.

This antibody enables precise identification and characterization of CXCR3-expressing cells in research related to immunology, inflammatory diseases, and cancer immunotherapy.With its validated performance in detecting human CXCR3, the PE-Cyanine7 Anti-Human CD183 (CXCR3) Antibody (G025H7) facilitates in-depth investigation of the biological functions and signaling pathways associated with this important chemokine receptor. Gain valuable insights into immune responses and inflammatory processes with this reliable and specific antibody, advancing your studies in immunology, oncology, and drug development.

Product Title:PE/Cyanine7 Anti-Human CD183/CXCR3 Antibody [G025H7]
SKU:AGEL2286
Size:20 Tests, 100 Tests, 200 Tests
Clone No:G025H7
Synonyms:CXCR3;GPR9;CXC-R3;CXCR-3;CKR-L2;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE/Cyanine7 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P49682
Gene ID:2833
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Human CXCR3, also known as GPR9, is a chemokine receptor that binds CXCL9, CXCL10, and CXCL11. It is a 38 kD seven-pass transmembrane receptor coupled to G-protein. CXCR3 is highly expressed by T cells (Th1), natural killer cells (NK cells), dendritic cells, mast cells, alveolar macrophages, eosinophils, and human airway epithelial cells. CXCR3 is important for effector lymphocyte recruitment into inflamed tissue in various inflammatory and autoimmune diseases, such as chronically inflamed liver, Crohn's disease, rheumatoid arthritis, multiple sclerosis, and inflammatory skin diseases.

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