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PE/Cyanine7 Anti-Human CD161 Antibody [HP-3G10] (AGEL2281)

SKU:
AGEL2281
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, κ
Clone:
HP-3G10
Conjugation:
PE/Cyanine7
€289 - €889
Frequently bought together:

Description

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PE/Cyanine7 Anti-Human CD161 Antibody [HP-3G10]

The PE-Cyanine7 Anti-Human CD161 Antibody (HP-3G10) offered by AssayGenie is a powerful tool for researchers studying the CD161 cell surface molecule. CD161, also known as NKR-P1A, is a C-type lectin receptor expressed on natural killer cells and certain subsets of T cells. This highly specific antibody, validated for human samples, allows for precise detection and analysis of CD161 in various cell types.The HP-3G10 antibody is ideal for use in flow cytometry, immunofluorescence, and other immunological techniques, providing valuable insights into the role of CD161 in immune responses and inflammatory processes. With its high reactivity and specificity, this antibody is a valuable asset for investigations into immune cell function, autoimmunity, infectious diseases, and immunotherapy research.

By targeting CD161 and elucidating its functions, researchers can deepen their understanding of immune regulation and potentially uncover new therapeutic targets for conditions such as autoimmune diseases, infections, and cancer. AssayGenie's PE-Cyanine7 Anti-Human CD161 Antibody (HP-3G10) is a reliable reagent that enhances the precision and reliability of experiments exploring the complexities of immune responses in health and disease.

Product Title:PE/Cyanine7 Anti-Human CD161 Antibody [HP-3G10]
SKU:AGEL2281
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HP-3G10
Synonyms:CLEC5B; NKRP1A;NKR-P1A;HNKR-P1a;KLRB1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE/Cyanine7 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q12918
Gene ID:3820
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD161 is a type II transmembrane glycoprotein, also known as NKR-P1A, that is expressed as a 40-44 kD homodimer. It is a member of the C-type lectin superfamily. CD161 is expressed on a majority of NK cells, NKT cells, and subsets of peripheral T cells and CD3+ thymocytes. It has been reported that Th17 cells are a subpopulation of CD4+CD161+CCR6+ cells. While the biological function of CD161 is not clear, it has been suggested to serve either as a stimulatory receptor or to inhibit NK cell-mediated cytotoxicity and cytokine production. LLT-1 (lectin-like transcript-1, also named as osteoclast inhibitory lectin or CLEC2D) is the ligand of CD161.

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