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PE/Cyanine7 Anti-Human CD16 Antibody [3G8] (AGEL2769)

SKU:
AGEL2769
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, κ
Clone:
3G8
Conjugation:
PE/Cyanine7
€219 - €699
Frequently bought together:

Description

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PE/Cyanine7 Anti-Human CD16 Antibody [3G8]

The PE-Cyanine7 Anti-Human CD16 Antibody (3G8) from AssayGenie (product link: www.assaygenie.com/pe-cyanine7-anti-human-cd16-antibody-3g8/) is a cutting-edge tool designed for researchers focusing on human CD16, a cell surface receptor essential for immune responses and cell communication. This antibody, optimized for flow cytometry applications, provides high specificity and sensitivity in detecting CD16 expression in various cell types.CD16, also known as Fc gamma receptor III (FcγRIII), plays a crucial role in mediating antibody-dependent cellular cytotoxicity (ADCC) and phagocytosis, making it a key target for studies in immunology, oncology, and infectious diseases.

By targeting CD16, researchers can gain valuable insights into immune cell activation, target cell recognition, and therapeutic antibody efficacy.With its superior performance in flow cytometry, the PE-Cyanine7 Anti-Human CD16 Antibody (3G8) enables precise identification and characterization of CD16-positive cell populations, facilitating in-depth analysis of immune responses and disease mechanisms. By utilizing this antibody, researchers can advance their understanding of immune cell function and develop innovative strategies for targeted therapies and immunotherapies.

Product Title:PE/Cyanine7 Anti-Human CD16 Antibody [3G8]
SKU:AGEL2769
Size:20 Tests, 100 Tests, 200 Tests
Clone No:3G8
Synonyms:FcγRIII;Fc gamma receptor;Fc gamma receptor 3;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE/Cyanine7 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P08637 O75015
Gene ID:941
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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